A lender would likely approve you up to $230,278
On $72,000 of gross income with $550 of existing monthly debt, the 28/36 rule supports about $1,610 a month toward housing. With $40,000 down at 6.65%, that reaches roughly $230,278 — a $190,278 loan at 17.4% down. Your resulting debt-to-income ratio would be 36%, and you are currently limited by the total debt.