Because both self-employment tax and income tax are calculated on net profit, every legitimate business expense saves you the combined rate — often 30% or more per dollar. That's a far better return than most personal deductions, and it's why disciplined record-keeping matters so much for the self-employed.
Commonly missed deductions include the home office (a specific square-footage or simplified calculation), business mileage, software and subscriptions, professional development, a portion of your phone and internet, and self-employed health insurance premiums. Retirement contributions through a SEP-IRA or Solo 401(k) reduce income tax on your profit as well, though not the SE tax — and they let the self-employed shelter far more than a standard IRA allows.